Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

PKC iota (Serine/threonine kinase)

Seq-ID:

P41743 [Homo sapiens]

Download:

Interaction Network(s):

STRING

NetworKIN

External Source(s):

Phosida

Phosida

MINT Interaction(s):

MINT-66072 PAR6A_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein kinase C activity, phospholipid binding, ATP binding, zinc ion binding, protein binding	endosome, polarisome, cytosol, nucleus	protein amino acid phosphorylation, protein targeting to membrane, vesicle-mediated transport, anti-apoptosis, establishment or maintenance of epithelial cell apical/basal polarity, secretion, cellular response to insulin stimulus, positive regulation of establishment of protein localization in plasma membrane, cellular membrane organization, positive regulation of glucose import, cell-cell junction organization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	256	DLLRVIGRGSYAKVLLVRLKK	SRC	11713277	LTP	0.00		-	S_TKc	0.09	1ZRZ	60.26%
Y	271	LVRLKKTDRIYAMKVVKKELV	SRC	11713277	LTP	0.00		-	S_TKc	0.17	1ZRZ	9.61%
Y	325	TESRLFFVIEYVNGGDLMFHM	SRC	11713277	LTP	0.00		-	S_TKc	0.04	1ZRZ	36.68%
T	400	MCKEGLRPGDTTSTFCGTPNY	-	18669648	HTP	0.00		-	S_TKc	0.37	1ZRZ	50.00%
T	401	CKEGLRPGDTTSTFCGTPNYI	-	18669648	HTP	0.00		-	S_TKc	0.37	1ZRZ	10.96%
S	402	KEGLRPGDTTSTFCGTPNYIA	-	18669648	HTP	0.00		-	S_TKc	0.35	1ZRZ	52.46%
T	403	EGLRPGDTTSTFCGTPNYIAP	-	15314172	LTP	0.00		-	S_TKc	0.35	1ZRZ	65.07%
T	403	EGLRPGDTTSTFCGTPNYIAP	-	18220336	HTP	0.00		-	S_TKc	0.35	1ZRZ	65.07%
T	403	EGLRPGDTTSTFCGTPNYIAP	-	18669648	HTP	0.00		-	S_TKc	0.35	1ZRZ	65.07%